Volume 8, Issue 3, September 2020, Page: 28-35
Toxoplasmosis Sero-Prevalence, Awareness and Risk Behavior Among Pregnant Women Following Antenatal Care in Asella Teaching and Referral Hospital, Asella, Ethiopia
Shimeles Adugna Elemo, Medical Laboratory Sciences Department, Collage of Health Sciences, Arsi University, Asella, Ethiopia
Received: Aug. 21, 2020;       Accepted: Sep. 3, 2020;       Published: Sep. 19, 2020
DOI: 10.11648/j.ijbse.20200803.12      View  74      Downloads  27
Abstract
Toxoplasmosis is caused by infection with the protozoan Toxoplasma gondii (T. gondii), an obligate intracellular parasite. The infections produced a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Toxoplasmosis is especially important among Immune-compromised patients and pregnant women. Infection of mothers during pregnancy by Toxoplasma gondii may have serious consequences for fetus ranging from miscarriage, central nervous system involvement, retinochoroditis, or at birth subclinical infection. Objectives: To determine Toxoplasmosis sero-prevalence, awareness and risk Behavior among pregnant women following antenatal care in Asella Teaching and Referral Hospital, Asella, Ethiopia. Methods: Institutional based quantitative cross sectional study design was conducted on sample size of 384 from December 1, 2018 to June 30, 2019. To collect the demographic and risk factor related data a pre-tested Structured, questionnaire was used. Serum sample, collected was tested for Toxoplasma Immunoglobulin G (IgG) and Toxoplasma Immunoglobulin M (IgM) antibodies using anti- IgG and IgM antibodies by Toxoplasma immune-chromatographic test (ICT) IgG-IgM test. To show association between the dependent and independent variables a bivariable and multivariable logistic regression model was applied allowing for p, 0.05 and the confidence interval 95%. Result: The overall sero- prevalence of T. gondii in the study area was 81.8%. Three hundred and fourteen (81.8%) of the pregnant women were IgG seropositive, fifty women (13%) were IgM seropositive. fifty women were positive for both IgG and IgM. None of the pregnant women were positive exclusively for IgG and IgM ani-bodies. eating raw meat (COR=3.480, 95%CI: 1.450-8.352; P=0.005, AOR=3.798, 95%CI: 1.249-11.550, P=0.19), using unpasteurized milk (COR=3.860, 95%CI: 2.118-7.037; P=0.000, AOR=3.907, 95% CI: 1.744-8.751, P=0.001), having three or more children (COR=2.194, 95%CI: 1.065-4.518; P=0.033) and Consumption of raw egg (COR=2.042, 95%CI: 1.049-3.974; P=0.036). Conclusion: The sero-prevalence of T. gondii antibodies was high among the pregnant women. Those who consumed raw meat and egg, unpasteurized milk and those who have three or more children were at higher risk of T. gondii infection. Hence, blood screening for Toxoplasmosis, health education and awareness creation among pregnant women should be done during antenatal follow up.
Keywords
Sero-prevalence, Pregnant Women, Risk Factors. T. gondii, Asella, Ethiopia
To cite this article
Shimeles Adugna Elemo, Toxoplasmosis Sero-Prevalence, Awareness and Risk Behavior Among Pregnant Women Following Antenatal Care in Asella Teaching and Referral Hospital, Asella, Ethiopia, International Journal of Biomedical Science and Engineering. Vol. 8, No. 3, 2020, pp. 28-35. doi: 10.11648/j.ijbse.20200803.12
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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